ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development
Senior Clinical Pharmacologist - 12 month Fixed Term Contract
(Director, Clinical Pharmacology)
We are currently seeking a Director, Clinical Pharmacology to join our diverse and dynamic team. As a Director, Clinical Pharmacology at ICON, you will play a pivotal role in leading the design, execution, and interpretation of clinical pharmacology studies to support the development of innovative therapies. You will ensure the strategic integration of pharmacokinetic and pharmacodynamic data into clinical trial designs, driving informed decision-making and advancing therapeutic development.
What You Will Be Doing:
Serve as a hands-on clinical pharmacologist, actively involved in study design, data analysis, and interpretation.
Develop and execute clinical pharmacology strategies to support dose-regimen selection, population targeting, biomarker utilization, and endpoint optimization to enable global product registration.
Design and execute modeling plans in collaboration with Pharmacometricians.
Contribute to pre-clinical study design to inform translational modeling.
Support first-in-human (FIH) study design, including SAD and MAD studies, and dose selection.
Prepare and contribute to regulatory submissions and respond to authority queries.
Align early on key development questions where clinical pharmacology principles can be applied.
Actively participate in project discussions, ensuring QCP² involvement meets key development goals.
Attend governance meetings and ensure flawless, timely execution of CP plans for efficient decision-making.
Maintain up-to-date knowledge of model-based drug development, clinical pharmacology, biopharmaceutics, PK/PD modeling, and related analytical sciences.
Develop and implement integrated strategies leveraging expertise across preclinical, clinical, and regulatory functions.
Coordinate outsourced clinical pharmacology activities effectively.
Your Profile:
PhD in Biological Sciences, Bioengineering, or a related field.
Minimum 13 years of pharmacology experience in pharmaceutical or related industries.
Proven hands-on experience in clinical pharmacology, including study design, PK/PD modeling, and data interpretation.
Fluent in written and spoken English with excellent communication skills.
Strong knowledge of innovative clinical pharmacokinetics, clinical pharmacology, and PK/PD modeling approaches in model-based drug development.
Thorough understanding of the clinical development process.
Proven ability to drive alignment around vision and strategy across departments.
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What ICON can offer you:
Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.
In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.
Our benefits examples include:
Various annual leave entitlements
A range of health insurance offerings to suit you and your family’s needs.
Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family’s well-being.
Life assurance
Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others.
Visit our careers site to read more about the benefits ICON offers.
At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here.
Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.
Are you a current ICON Employee? Please click here to apply
Top Skills
ICON plc Dublin, Dublin, IRL Office
ICON plc, South County Business Park, Dublin, Ireland
